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Differentiation of ATTR amyloidosis based on abdominothoracic organ-specific uptakeof 124I-AT-01 (124I-p5+14)assessed by PET/CT imaging

Sep 6, 2022 Posters & Publications

AUTHORS: Stuckey, Alan1, Martin, Emily1, Heidel, R Eric1, Kennel, Stephen1, Perk, Timothy2, Weisman, Amy J2, Wall, Jonathan1 1 University of Tennessee Graduate School of Medicine, USA 2 AIQ Solutions, USA Click Here to View...

Quantitative changes in organ-specific amyloid load in a patient with AL amyloidosis,measured by 124I-AT-01 PET/CT imaging, correlate with serumbiomarkers

Sep 6, 2022 Posters & Publications

AUTHORS: Stuckey, Alan1, Martin, Emily1, Heidel, R Eric1, Kennel, Stephen1, Perk, Timothy2, Weisman, Amy J2, Wall, Jonathan1 1 University of Tennessee Graduate School of Medicine, USA 2 AIQ Solutions, USA Click Here to View...

Quantification of left ventricular amyloid using 124I-p5+14 (AT-01) and 18F-florbetapir positron emission tomography in AL and ATTR amyloidosis

Sep 6, 2022 Posters & Publications

AUTHORS: Clerc, Olivier F.1, Falk, Rodney H.1, Cuddy, Sarah A. M.1, Benz, Dominik C. 1, Taylor, Alexandra1, Canseco Neri, Jocelyn1, Robertson, Matthew2, Newsom, James D.2, Kijewski, Marie Foley2, Dicarli, Marcelo F. 2, Bianchi, Giada1, Dorbala, Sharmila1,2 1 Cardiac...

Results of the first-in-human PET/CT imaging study of the amyloid-reactive peptide 124I-AT-01 (124I-p5+14) for the detection of systemic amyloidosis

Sep 5, 2022 Posters & Publications

AUTHORS: Jonathan S. Wall1, Emily B. Martin1, Alan Stuckey1, Dustin Powell2, Tina Richey1, Angela Williams1, R. Eric Heidel3, Ronald Lands1, Stephen J. Kennel1 Departments of Medicine1, Radiology2 and Surgery3, University of Tennessee Graduate School of Medicine, TN,...

Pan-amyloid reactivity of radioiodinated peptide 124I-AT-01 in patients with systemic amyloidosis demonstrated by PET/CT imaging

Sep 5, 2022 Posters & Publications

AUTHORS: Emily B. Martin1, Alan Stuckey1, Dustin Powell2, Ronald Lands2, Spencer Guthrie3, Stephen J. Kennel1, and Jonathan S. Wall1 1 University of Tennessee Graduate School of Medicine, Knoxville, TN, USA 2 University of Tennessee Medical Center, Knoxville, TN, USA...
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Recent Posts

  • Accurate Quantitation of Cardiac Amyloidosis by 124I-Evuzamitide Compared to Extracellular Volume
  • Exploring cardiac uptake of the SPECT radiotracer, 99mTc-p5+14 (AT-05), in patients with amyloidosis – Significant correlations exist between structural or functional parameters and signal-to-background measurements.
  • Extracardiac uptake of the SPECT/CT imaging agent, 99mTc-p5+14 (AT-05), in patients with AL or ATTR cardiac amyloidosis
  • 99mTc-p5+14 (AT-05) is a pan-amyloid imaging agent that effectively detects cardiac amyloid by both planar and SPECT/CT imaging at 1 h post-injection with a high signal-to-background ratio
  • A Tale of Two Tracers – A Qualitative Comparison of the PET and SPECT Amyloid-Imaging Agents, 124I-evuzamitide (AT-01) and 99mTc-p5+14 (AT-05), that are Derived from the Same Synthetic Amyloid-Binding Peptide, p5+14

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