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Preclinical characterization of AT-04, a pan-amyloid-binding Fc domain-peptide fusion, to serve as an opsonin for macrophage-mediated clearance of amyloid deposits

Sep 7, 2022 Posters & Publications

AUTHORS: James S. Foster1, Spencer Guthrie2, Michael L. Klein2, Gregory Bell2, Suganya Selvarajah2, Angela D. Williams1, Manasi Balachandran1, Joseph W. Jackson1, Alan Stuckey1, Emily Martin1, Sallie Macy1, D. Craig Wooliver1, R. Eric Heidel1, Stephen J. Kennel1,...

Recent Posts

  • Attralus Has Been Granted U.S. FDA Fast Track Designation for Zamubafusp Alfa (AT-02) for the Treatment of AL Amyloidosis
  • Attralus Therapeutic Zamubafusp Alfa (AT-02) Receives U.S. FDA Orphan Drug Designation for the Treatment of AL Amyloidosis
  • Bayer to expand into molecular imaging with acquisition of innovative pan-amyloid radiotracers from Attralus
  • Renal and cardiac responses in a phase 1/2 study of AT-02, a novel pan-amyloid depleter IgG fusion protein for the treatment of patients with AL amyloidosis
  • Attralus To Present Phase 1/2 Data on Its Pan Amyloid Depleter at the 67th American Society of Hematology (ASH) Annual Meeting and Exposition

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